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  • Haemophilus influenzae type┬áB vaccine (Hib vaccine or PRP vaccine) is a conjugate vaccine developed for the prevention of invasive disease caused by Haemophilus influenzae type b bacteria. The Centers for Disease Control and Prevention (CDC) has recommended the use of the Hib vaccine. Due to routine use of the Hib vaccine in the U.S. from 1980 to 1990, the incidence of invasive Hib disease has decreased from 40-100 per 100,000 children down to 1.3 per 100,000. Vaccinations against Haemophilus influenzae (Hib) have decreased early childhood meningitis significantly in developed countries and recently in developing countries. The first Hib vaccine licensed was a pure polysaccharide vaccine, first marketed in the US in 1985. Similar to other polysaccharide vaccines, immune response to the vaccine was highly age dependent. Children under 18 months of age did not produce a positive response for this vaccine. As a result, the age group with the highest incidence of Hib disease was...
  • Hib vaccine
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